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På grund av risken fileör serotonergt syndrom bör Petidin Meda inte användas i kombination med serotonerga läkemedel (se avsnitt Interaktioner). Meperidine is not really proposed as a primary option analgesic by The American discomfort Society and ISMP (2007); if no other choices, limit use in acute pain to ≤48hr; doses should not exceed 60

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